BDBM50027796 2-(Sulfanilylamino)thiazole::2-(p-Aminobenzenesulfonamido)thiazole::2-(p-Aminobenzenesulphonamido)thiazole::2-Sulfanilamidothiazol::2-Sulfanilamidothiazole::2-Sulfonamidothiazole::4-Amino-N-2-thiazolylbenzenesulfonamide::4-amino-N-1,3-thiazol-2-ylbenzenesulfonamide::CHEMBL437::N(1)-2-Thiazolylsulfanilamide::Sulfanilamidothiazole::Sulfathiazole::Sulphathiazole::cid_5340

SMILES Nc1ccc(cc1)S(=O)(=O)Nc1nccs1

InChI Key InChIKey=JNMRHUJNCSQMMB-UHFFFAOYSA-N

Data  5 IC50

PDB links: 4 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50027796   

TargetRecBCD enzyme subunit RecD(Escherichia coli str. K-12 substr. MG1655)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50027796(2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...)
Affinity DataIC50:  7.59E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50027796(2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...)
Affinity DataIC50:  6.90E+4nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50027796(2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa harboring GFP-fused quorum sensing lasB measured every 15 mins up to 12 hrs by GFP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Prestwick Chemical

Curated by ChEMBL
LigandPNGBDBM50027796(2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibitory concentration against Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50027796(2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...)
Affinity DataIC50:  4.30E+5nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed