BDBM50029426 CHEMBL24675::[2-(3,4-Dimethoxy-phenyl)-ethyl]-[4-(4-methoxy-phenyl)-4H-benzo[b]pyrrolo[1,2-d][1,4]thiazin-1-ylmethyl]-methyl-amine
SMILES COc1ccc(cc1)C1Sc2ccccc2-n2c(CN(C)CCc3ccc(OC)c(OC)c3)ccc12
InChI Key InChIKey=KIYASJXFIUZQLU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50029426
Affinity DataKi: 8.30nMAssay Description:Calcium antagonistic activity by measuring [3H]-nitrendipine displacement from rat heart L-type [Ca2+] channelMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptorMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena
Curated by ChEMBL
Universita' Degli Studi Di Siena
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptorMore data for this Ligand-Target Pair