BDBM50030110 CHEMBL3343528

SMILES NC(=O)c1cncc(Nc2cccc3ccccc23)c1

InChI Key InChIKey=CCBBNNPSDVJJJI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030110   

TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030110(CHEMBL3343528)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of catalytically active human SIRT3 (102 to 399 amino acids) expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030110(CHEMBL3343528)
Affinity DataIC50:  4.09E+4nMAssay Description:Inhibition of full length human SIRT1 expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-methylcoumarin (AMC)-labeled peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030110(CHEMBL3343528)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of full length human SIRT2 expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-methylcoumarin (AMC)-labeled peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed