BDBM50031771 (R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamoyl)-heptanedioic acid 1-hydroxyamide 7-(phenethyl-amide)::(R)-N1-hydroxy-N2-((S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl)-N5-phenethylpentane-1,2,5-tricarboxamide::CHEMBL86797

SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCC(=O)NCCc1ccccc1)CC(=O)NO

InChI Key InChIKey=WSGLDBYEABEDRD-YADHBBJMSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50031771   

TargetStromelysin-1(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50031771((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  6nMAssay Description:Inhibitory potency against human stromelysin, MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50031771((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  6nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50031771((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  6nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50031771((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  32nMAssay Description:Inhibition of human neutrophil collagenase, matrix metalloproteinase-8More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50031771((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  32nMAssay Description:Inhibition of human neutrophil collagenase(HNC), MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50031771((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi: <100nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50031771((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50031771((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibitory potency against human fibroblast collagenase, MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed