BDBM50039966 1-[(S)-2-(Methyl-phenylacetyl-amino)-2-phenyl-ethyl]-pyrrolidinium::CHEMBL94734::N-Methyl-2-phenyl-N-((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide

SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccccc1

InChI Key InChIKey=OVZWUDZIAAHNFG-HXUWFJFHSA-N

Data  1 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50039966   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50039966(1-[(S)-2-(Methyl-phenylacetyl-amino)-2-phenyl-ethy...)
Affinity DataKi:  5.80nMAssay Description:Inhibitory constant against human Opioid receptor kappa using [3H]-diprenorphine as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50039966(1-[(S)-2-(Methyl-phenylacetyl-amino)-2-phenyl-ethy...)
Affinity DataIC50:  1.40nMAssay Description:Tested for inhibitory concentration against [3H]U-69593 binding at sites of kappa-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50039966(1-[(S)-2-(Methyl-phenylacetyl-amino)-2-phenyl-ethy...)
Affinity DataIC50:  46nMAssay Description:Inhibition of cytochrome P450 2D6 was determined using MAMC (7-methoxy-4-aminomethyl-coumarin) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50039966(1-[(S)-2-(Methyl-phenylacetyl-amino)-2-phenyl-ethy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50039966(1-[(S)-2-(Methyl-phenylacetyl-amino)-2-phenyl-ethy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50039966(1-[(S)-2-(Methyl-phenylacetyl-amino)-2-phenyl-ethy...)
Affinity DataEC50:  50nMAssay Description:Inhibitory constant against human Opioid receptor kappa using [3H]diprenorphine as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed