BDBM50041179 2-{4-[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylmethyl)-amino]-benzoylamino}-pentanedioic acid::CHEMBL17383
SMILES Nc1nc(N)c2c(CNc3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)coc2n1
InChI Key InChIKey=ACXZKUHGYNILFP-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50041179
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound for TS in humanMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound for TS in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration of the compound for DHFR in Pneumocystis cariniiMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration of the compound against L. casei AICAR formyltransferaseMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration of the compound in glycinamide ribonucleotide formyltransferase (GARFT) L. caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of P. carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibitory concentration of the compound for DHFR in recombinant humanMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory concentration of the compound for DHFR in rat liverMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration of the compound for DHFR in Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of T. gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibitory concentration of the compound for DHFR in Lactobacillus caseiMore data for this Ligand-Target Pair