BDBM50043685 CHEMBL3355549::US10047093, 8-51::US10392392, Example 8-51::US10875864, EX. 8-51::US9416132, 8-51
SMILES FC(F)(F)Oc1cccc(c1)-c1cnn2ccc(NCC3CCS(=O)(=O)CC3)nc12
InChI Key InChIKey=IKSRTKYPEDDPBA-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50043685
Affinity DataIC50: 148nMT: 2°CAssay Description:These assays are set up in duplicate 50 ul volumes in white, flat bottom 96 well plates. Inhibitors are added to the solution of 1× kinase buff...More data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Inhibition of Pim1 (unknown origin) using luciferase-luciferin based ATP detection reagent by Kinase-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
Affinity DataIC50: 148nMT: 2°CAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.16E+3nMAssay Description:Inhibition of Pim2 (unknown origin) using luciferase-luciferin based ATP detection reagent by Kinase-Glo assayMore data for this Ligand-Target Pair