BDBM50047086 2-{3-[4-(1-Methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL19111

SMILES Cn1cc(C2=CCN(CCCN3c4cccc5cccc(c45)S3(=O)=O)CC2)c2ccccc12

InChI Key InChIKey=NKSXAKPRNJHCLU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047086   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Centre De Recherches De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50047086(2-{3-[4-(1-Methyl-1H-indol-3-yl)-3,6-dihydro-2H-py...)
Affinity DataIC50: >100nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre De Recherches De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50047086(2-{3-[4-(1-Methyl-1H-indol-3-yl)-3,6-dihydro-2H-py...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed