BDBM50056362 3-Amino-5,6-dimethyl-2-[3-(4-pyrimidin-2-yl-piperazin-1-yl)-propylsulfanyl]-3H-thieno[2,3-d]pyrimidin-4-one::CHEMBL12177
SMILES Cc1sc2nc(SCCCN3CCN(CC3)c3ncccn3)n(N)c(=O)c2c1C
InChI Key InChIKey=FBVVCNRRXMQYPZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50056362
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampus membranesMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Università
Curated by ChEMBL
Università
Curated by ChEMBL
Affinity DataKi: 434nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of rat cortex membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor in rat cortical memb...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in pig cortical mem...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-BRL-43694 binding to 5-hydroxytryptamine 3 receptor in rat cortical membra...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-SCH-23,390 binding to Dopamine receptor D1 in rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair