BDBM50057777 CHEMBL3323010::US9598387, Compound 112::US9969743, 112

SMILES CC(C)(C)c1nc(cc(n1)N1CCN(CCCCNC(=O)c2cn3ccccc3n2)CC1)C1CC1

InChI Key InChIKey=QSQIAXNZWRLSSO-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50057777   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057777(CHEMBL3323010 | US9598387, Compound 112 | US996974...)
Affinity DataKi:  8.40nMAssay Description:Displacement of [125I]IABN from human D3R expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057777(CHEMBL3323010 | US9598387, Compound 112 | US996974...)
Affinity DataKi:  8.40nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057777(CHEMBL3323010 | US9598387, Compound 112 | US996974...)
Affinity DataKi:  8.40nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057777(CHEMBL3323010 | US9598387, Compound 112 | US996974...)
Affinity DataKi:  191nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057777(CHEMBL3323010 | US9598387, Compound 112 | US996974...)
Affinity DataKi:  191nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057777(CHEMBL3323010 | US9598387, Compound 112 | US996974...)
Affinity DataKi:  191nMAssay Description:Displacement of [125I]IABN from human D2LR expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed