BDBM50059791 CHEMBL3393897

SMILES FC(F)(F)c1cc(NC(=O)c2ccc(Cl)c(c2)C(=O)Nc2ccc(nc2)-c2ncc[nH]2)ccc1Cl

InChI Key InChIKey=WLMAHUGJWNORQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059791   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50059791(CHEMBL3393897)
Affinity DataIC50:  2.34E+4nMAssay Description:Inhibition of human recombinant VEGFR2 incubated for 1 hr using [gamma-32P]ATP by top count assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50059791(CHEMBL3393897)
Affinity DataIC50:  531nMAssay Description:Inhibition of BRAF (unknown origin) incubated for 15 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed