BDBM50062381 3-(3-Cyclopentyloxy-4-methoxy-phenyl)-5-methyl-4,5-dihydro-isoxazole-5-carboxylic acid hydroxyamide::CHEMBL91551

SMILES COc1ccc(cc1OC1CCCC1)C1=NOC(C)(C1)C(=O)NO

InChI Key InChIKey=SKSQSCQKTAQENI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50062381   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50062381(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-5-methyl-4,5...)
Affinity DataIC50:  9.80nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase type 4A (PDE4A).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50062381(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-5-methyl-4,5...)
Affinity DataIC50:  10nMAssay Description:Compound was evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50062381(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-5-methyl-4,5...)
Affinity DataIC50:  10.9nMAssay Description:Inhibition of recombinant human Phosphodiesterase 4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50062381(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-5-methyl-4,5...)
Affinity DataIC50:  95.2nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed