BDBM50062714 (2R,3R)-3-[(Biphenyl-4-carbonyl)-amino]-2-(3-carbamimidoyl-benzyl)-5-phenyl-pentanoic acid methyl ester::CHEMBL45407

SMILES COC(=O)[C@H](Cc1cccc(c1)C(N)=N)[C@@H](CCc1ccccc1)NC(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=JFZUBUPLMKFLQR-LOYHVIPDSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50062714   

TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062714((2R,3R)-3-[(Biphenyl-4-carbonyl)-amino]-2-(3-carba...)
Affinity DataKi:  21nMAssay Description:In vitro inhibitory activity against human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062714((2R,3R)-3-[(Biphenyl-4-carbonyl)-amino]-2-(3-carba...)
Affinity DataKi:  67nMAssay Description:In vitro inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062714((2R,3R)-3-[(Biphenyl-4-carbonyl)-amino]-2-(3-carba...)
Affinity DataKi:  810nMAssay Description:In vitro inhibitory activity against human Coagulation factor IIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062714((2R,3R)-3-[(Biphenyl-4-carbonyl)-amino]-2-(3-carba...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed