BDBM50064463 CHEMBL3401177
SMILES Fc1ccc(cc1)-n1ccc2nc(COc3ccccc3)cn2c1=O
InChI Key InChIKey=SCXUQPKHWUFDNI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50064463
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataEC50: 309nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Negative allosteric modulation at mGluR3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR2 (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataEC50: 310nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR4 (unknown origin)More data for this Ligand-Target Pair