BDBM50072570 (2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxo-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL110527

SMILES CC(C)C[C@H]([C@H](CC=C)C(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(C)=O

InChI Key InChIKey=DOECLBQWTWHNID-OTWHNJEPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072570   

TargetMatrilysin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50072570((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxo-propyl)-N...)
Affinity DataIC50:  45nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloproteinase 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50072570((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxo-propyl)-N...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloproteinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50072570((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxo-propyl)-N...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase 2 isolated from human HT-1080 fibrosarcoma cells induced with TNFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed