BDBM50074992 (E)-N-({[4-Chloro-2-methoxy-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-(4-trifluoromethyl-phenyl)-acrylamide::CHEMBL113465

SMILES COc1c(COc2cccc3ccc(C)nc23)c(Cl)ccc1N(C)C(=O)CNC(=O)\C=C\c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=TTZDPFYXDMUHJE-MHWRWJLKSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074992   

TargetB2 bradykinin receptor(Cavia porcellus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50074992((E)-N-({[4-Chloro-2-methoxy-3-(2-methyl-quinolin-8...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Cavia porcellus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50074992((E)-N-({[4-Chloro-2-methoxy-3-(2-methyl-quinolin-8...)
Affinity DataIC50:  22nMAssay Description:Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Cavia porcellus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50074992((E)-N-({[4-Chloro-2-methoxy-3-(2-methyl-quinolin-8...)
Affinity DataEC50:  55nMAssay Description:Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed