BDBM50075351 4-(5,5-Dimethyl-8-o-tolyl-5,6-dihydro-naphthalen-2-ylethynyl)-benzoic acid::CHEMBL156940

SMILES Cc1ccccc1C1=CCC(C)(C)c2ccc(cc12)C#Cc1ccc(cc1)C(O)=O

InChI Key InChIKey=VHMFYEZAGYYIKJ-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075351   

TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50075351(4-(5,5-Dimethyl-8-o-tolyl-5,6-dihydro-naphthalen-2...)
Affinity DataKd:  35nMAssay Description:Ability to displace 3[H]-(all-E)-retinoic acid (5 nM) from Retinoic acid receptor gamma using transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50075351(4-(5,5-Dimethyl-8-o-tolyl-5,6-dihydro-naphthalen-2...)
Affinity DataKd:  29nMAssay Description:Ability to displace 3[H]-(all-E)-retinoic acid (5 nM) from beta retinoic acid receptor (beta RAR) using transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50075351(4-(5,5-Dimethyl-8-o-tolyl-5,6-dihydro-naphthalen-2...)
Affinity DataKd:  103nMAssay Description:Ability to displace 3[H]-(all-E)-retinoic acid (5 nM) from alpha retinoic acid receptor (alpha RAR) using transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed