BDBM50076724 (S)-5-(4-Methylamino-phenyl)-2-(naphthalene-2-sulfonylamino)-pent-4-ynoic acid cyclopentyl-methyl-amide::CHEMBL415479

SMILES CNc1ccc(cc1)C#CC[C@H](NS(=O)(=O)c1ccc2ccccc2c1)C(=O)N(C)C1CCCC1

InChI Key InChIKey=RCTWBEIFOZSNKC-MHZLTWQESA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50076724   

TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076724((S)-5-(4-Methylamino-phenyl)-2-(naphthalene-2-sulf...)
Affinity DataKi:  19nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076724((S)-5-(4-Methylamino-phenyl)-2-(naphthalene-2-sulf...)
Affinity DataKi:  8.70E+3nMAssay Description:Inhibitory activity of the compound against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076724((S)-5-(4-Methylamino-phenyl)-2-(naphthalene-2-sulf...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibitory activity of the compound against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076724((S)-5-(4-Methylamino-phenyl)-2-(naphthalene-2-sulf...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076724((S)-5-(4-Methylamino-phenyl)-2-(naphthalene-2-sulf...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity of the compound against tissue type plasminogen activator (t-PA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed