BDBM50081092 CHEMBL85238::N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2-((S)-3-cyclohexylmethanesulfonylamino-7-methoxy-2-oxo-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-acetamide; TFA

SMILES COc1ccc2N(CC(=O)N[C@H]3CCCN(C3O)C(N)=N)C(=O)[C@H](CCc2c1)NS(=O)(=O)CC1CCCCC1

InChI Key InChIKey=DRTWJAWLWULICG-GAIPOIILSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50081092   

TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081092(CHEMBL85238 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  1.90nMAssay Description:In vitro inhibitory activity of the compound against human enzyme Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081092(CHEMBL85238 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  829nMAssay Description:In vitro inhibitory activity of the compound against human enzyme thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081092(CHEMBL85238 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  9.90nMAssay Description:In vitro inhibitory activity against human prothrombinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081092(CHEMBL85238 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081092(CHEMBL85238 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibitory activity of the compound against human enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed