BDBM50094515 (S)-1,1,1-trifluoro-3-((3-phenoxyphenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)propan-2-ol::1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,2,2-tetrafluoro-ethoxy)-benzyl]-amino}-propan-2-ol::CHEMBL340310

SMILES O[C@@H](CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccccc2)c1)C(F)(F)F

InChI Key InChIKey=XNYMOOHZPFZFJE-NRFANRHFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50094515   

TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094515((S)-1,1,1-trifluoro-3-((3-phenoxyphenyl)(3-(1,1,2,...)
Affinity DataIC50:  2.00E+4nMAssay Description:Tested for inhibiting CETP-mediated transfer of [3H]-CE from HDL to LDL in vitro under buffered assay conditions in human serum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094515((S)-1,1,1-trifluoro-3-((3-phenoxyphenyl)(3-(1,1,2,...)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human CETP-mediated transfer of [3H]-CE from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Oryctolagus cuniculus)
Al-Zaytoonah Private University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50094515((S)-1,1,1-trifluoro-3-((3-phenoxyphenyl)(3-(1,1,2,...)
Affinity DataIC50:  800nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094515((S)-1,1,1-trifluoro-3-((3-phenoxyphenyl)(3-(1,1,2,...)
Affinity DataIC50:  2.00E+4nMAssay Description:Concentration required for 50% Inhibition against Cholesteryl ester transfer protein in presence of human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094515((S)-1,1,1-trifluoro-3-((3-phenoxyphenyl)(3-(1,1,2,...)
Affinity DataIC50:  800nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed