BDBM50100280 4-Imidazol-1-ylmethyl-2-phenethyloxy-benzonitrile::CHEMBL22454

SMILES N#Cc1ccc(Cn2ccnc2)cc1OCCc1ccccc1

InChI Key InChIKey=JVQYMSCCLBZQOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100280   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50100280(4-Imidazol-1-ylmethyl-2-phenethyloxy-benzonitrile ...)
Affinity DataIC50:  860nMAssay Description:Inhibition of rate of incorporation of [3H]-FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50100280(4-Imidazol-1-ylmethyl-2-phenethyloxy-benzonitrile ...)
Affinity DataIC50:  7.00E+3nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in cultured v-Ha-ras-transformed RAT1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed