BDBM50100280 4-Imidazol-1-ylmethyl-2-phenethyloxy-benzonitrile::CHEMBL22454
SMILES N#Cc1ccc(Cn2ccnc2)cc1OCCc1ccccc1
InChI Key InChIKey=JVQYMSCCLBZQOV-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50100280
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibition of rate of incorporation of [3H]-FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in cultured v-Ha-ras-transformed RAT1 cellsMore data for this Ligand-Target Pair