BDBM50105731 (S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbaldehyde::CHEMBL316983
SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O
InChI Key InChIKey=RIOOLQVLOZQLQJ-ZDUSSCGKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 29 hits for monomerid = 50105731
Affinity DataKi: 5.30nMAssay Description:High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Binding affinity (high) towards human dopamine receptor 3 against radioligand [3H]spiperone, expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D4.4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:High binding affinity towards human dopamine receptor 4.4 expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:High binding affinity towards human dopamine receptor 2 (short) expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D2S expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:High binding affinity towards human dopamine receptor 2 (long) expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Low inhibition constant against [3H]-spiperone binding to human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Low binding affinity towards human dopamine receptor 3 expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Low binding affinity towards human dopamine receptor 4.4 expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Low inhibition constant against [3H]-spiperone binding to human Dopamine receptor D4.4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Low inhibition constant against [3H]-spiperone binding to human Dopamine receptor D2S expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Binding affinity (low) towards human dopamine receptor 2 short against radioligand [3H]spiperone, expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Binding affinity (low) towards human dopamine receptor 2 long against radioligand [3H]spiperone, expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Low inhibition constant against [3H]-spiperone binding to human Dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition constant against [3H]-SCH-23,390 binding to Dopamine receptor D1 in bovine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Binding affinity (low) towards bovine dopamine receptor 1 by using [3H]-SCH- 23390 (0.3 nM) as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.60E+4nMAssay Description:In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 79nMAssay Description:Effective concentration to stimulate rat Dopamine receptor D2S mediated [3H]-thymidine incorporation into growing cells using mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Effective concentration to stimulate human Dopamine receptor D3 mediated [3H]-thymidine incorporation into growing cells using mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.20E+3nMAssay Description:Effective concentration to stimulate human Dopamine receptor D4.2 mediated [3H]-thymidine incorporation into growing cells using mitogenesis assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Effective concentration to stimulate rat Dopamine receptor D2L mediated [3H]-thymidine incorporation into growing cells using mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Effective concentration against dopamine D3 receptorMore data for this Ligand-Target Pair