BDBM50107976 6-[(9H-Fluoren-2-ylamino)-methyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL150082

SMILES Cc1c(CNc2ccc-3c(Cc4ccccc-34)c2)cnc2nc(N)nc(N)c12

InChI Key InChIKey=CJEKYVLLXPZBHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107976   

TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107976(6-[(9H-Fluoren-2-ylamino)-methyl]-5-methyl-pyrido[...)
Affinity DataIC50:  0.860nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex diihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107976(6-[(9H-Fluoren-2-ylamino)-methyl]-5-methyl-pyrido[...)
Affinity DataIC50:  6.70nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed