BDBM50113628 CHEMBL431511::[5-(4-Fluoro-phenylcarbamoyl)-pyridin-2-ylsulfanyl]-acetic acid methyl ester
SMILES COC(=O)CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1
InChI Key InChIKey=SHLGVUBRPWNMLF-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50113628
Affinity DataIC50: 42nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Antagonist activity at CXCR2 in human neutrophils assessed as reduction in GRO-alpha mediated chemotaxisMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]-IL-8 from CHO cell membranes expressing human CX3C chemokine receptor 2More data for this Ligand-Target Pair