BDBM50123206 2-(3-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol::CHEMBL24950

SMILES Oc1ccc2c(C=C(c3cccc(O)c3)C22Cc3ccccc3C2)c1

InChI Key InChIKey=NBNSBPOETAKHET-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50123206   

TargetEstrogen receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123206(2-(3-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol |...)
Affinity DataIC50:  34nMAssay Description:Binding affinity for Rat Estrogen receptor-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123206(2-(3-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol |...)
Affinity DataIC50:  28nMAssay Description:Binding affinity for Human Estrogen receptor-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123206(2-(3-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol |...)
Affinity DataIC50:  28nMAssay Description:Binding affinity for estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123206(2-(3-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol |...)
Affinity DataIC50:  23nMAssay Description:Binding affinity for Human Estrogen receptor-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123206(2-(3-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol |...)
Affinity DataIC50:  35nMAssay Description:Binding affinity for estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123206(2-(3-hydroxyphenyl)-1,2'-spirobi[1H-indene]-5-ol |...)
Affinity DataIC50:  29nMAssay Description:Binding affinity foor Rat Estrogen receptor-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed