BDBM50132451 3-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)-N-methyl-2-oxoindoline-5-carboxamide::3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-carboxylic acid methylamide::CHEMBL318079
SMILES CNC(=O)c1ccc2NC(=O)\C(=C/c3cn(C)c4ccc(OC)cc34)c2c1
InChI Key InChIKey=PFAPJAYUYRSASC-MFOYZWKCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50132451
Affinity DataIC50: 145nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 145nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Inhibition of human Syk expressed in Kluyveromyces lactis using Biot-(BA)3-DEEYEIP-NH2 as substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 145nMAssay Description:Inhibition of human Syk expressed in Kluyveromyces lactis using Biot-(BA)3-DEEYEIP-NH2 as substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Inhibition of SYK in rat RBL2H3 cells assessed as reduction in DNP-BSA-stimulated Fcepsilon receptor 1-mediated 5-HT releaseMore data for this Ligand-Target Pair