BDBM50134655 (6-Hydroxy-1H-indol-2-yl)-(4-phenyl-piperidin-1-yl)-methanone::(6-hydroxy-1H-indole-2-yl)-(4-phenylpiperidine-1-yl)-methanone::CHEMBL338104

SMILES Oc1ccc2cc([nH]c2c1)C(=O)N1CCC(CC1)c1ccccc1

InChI Key InChIKey=XLJLDVFESVWDSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134655   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134655((6-Hydroxy-1H-indol-2-yl)-(4-phenyl-piperidin-1-yl...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134655((6-Hydroxy-1H-indol-2-yl)-(4-phenyl-piperidin-1-yl...)
Affinity DataIC50: >8.00E+3nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed