BDBM50138759 5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,2,4]triazole-1-carboxylic acid dimethylamide::CHEMBL130478::N,N-dimethyl-5-(methylthio)-3-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazole-1-carboxamide

SMILES CSc1nc(nn1C(=O)N(C)C)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=FBOHEFQKBNWFPO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50138759   

TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138759(5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...)
Affinity DataIC50:  100nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138759(5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50138759(5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...)
Affinity DataIC50:  1.76nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138759(5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of HSL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138759(5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138759(5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...)
Affinity DataIC50:  800nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed