BDBM50140045 CHEMBL3764836
SMILES FC(F)(F)c1cccc(CNC(=O)[C@H](CCCCNC2CC2c2ccccc2)NC(=O)c2ccc(cc2)-c2ccccc2)c1
InChI Key InChIKey=SVRXJVGEJNTFDZ-OMYKBPHGSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50140045
Affinity DataIC50: >5.40E+5nMAssay Description:Inhibition of recombinant human LSD2 using H3K4 peptide as substrate assessed as decrease in H3K4 demethylation after 1 hr by mass spectroscopic anal...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Waseda University
Curated by ChEMBL
Waseda University
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MAO-B expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazolecarboxylic ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazolecarboxylic ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Waseda University
Curated by ChEMBL
Waseda University
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of N-terminal hexahistidine-tagged human LSD1 (1 to 852 amino acids) expressed in Escherichia coli BL21 (DE3) cells using H3K4me2 peptide ...More data for this Ligand-Target Pair