BDBM50147081 1-Isoquinolin-5-yl-3-[2-(4-trifluoromethoxy-phenyl)-ethyl]-urea::CHEMBL105252

SMILES FC(F)(F)Oc1ccc(CCNC(=O)Nc2cccc3cnccc23)cc1

InChI Key InChIKey=YHSHJMCQJBIORT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50147081   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50147081(1-Isoquinolin-5-yl-3-[2-(4-trifluoromethoxy-phenyl...)
Affinity DataKi:  6nMAssay Description:Binding affinity towards human vanilloid receptor subtype 1 expressed in HEK293 cell membrane using [3H]-RTX as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50147081(1-Isoquinolin-5-yl-3-[2-(4-trifluoromethoxy-phenyl...)
Affinity DataIC50:  11nMAssay Description:Antagonistic activity towards human vanilloid receptor subtype 1 expressed in HEK293 cell membrane, as inhibition of agonist-induced intracellular [C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed