BDBM50148236 4-(2-Methoxymethyl-pyrrolidin-1-yl)-but-2-ynoic acid [4-(3-bromo-phenylamino)-3-cyano-quinolin-6-yl]-amide::CHEMBL117324

SMILES COC[C@@H]1CCCN1CC#CC(=O)Nc1ccc2ncc(C#N)c(Nc3cccc(Br)c3)c2c1

InChI Key InChIKey=CCUWFRBLNGOQSJ-QFIPXVFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148236   

TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50148236(4-(2-Methoxymethyl-pyrrolidin-1-yl)-but-2-ynoic ac...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50148236(4-(2-Methoxymethyl-pyrrolidin-1-yl)-but-2-ynoic ac...)
Affinity DataIC50:  150nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed