BDBM50149910 CHEMBL3769561::US10273223, Compound B-153::US9637472, Compound B-153
SMILES Cc1cc(C)c(CNC(=O)c2cc(nc3n(C)ncc23)C2=CC(C)(C)NC(C)(C)C2)c(=O)[nH]1
InChI Key InChIKey=MYAWTCZOHZPHSF-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50149910
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of methyltransferase activity of human EZH2 using chicken oligonucleotide as substrate by pull down assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:eneral Procedure for Wild-Type PRC2 Enzyme Assay on Oligonucleosome Substrate. The assays was performed in a buffer consisting of 20 mM bicine (pH=7....More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Recombinant PRC2 Enzymes. Human PRC2 enzymes were purified as 4-component enzyme complexes co-expressed in Spodoptera frugiperda (sf9) cells using a ...More data for this Ligand-Target Pair