BDBM50151747 (3S,4R)-4-[4-(2,5-Dichloro-benzyloxy)-benzenesulfonyl]-3-hydroxy-tetrahydro-pyran-3-carboxylic acid hydroxyamide::CHEMBL360704

SMILES ONC(=O)[C@@]1(O)COCC[C@H]1S(=O)(=O)c1ccc(OCc2cc(Cl)ccc2Cl)cc1

InChI Key InChIKey=LPGGJWIOKRQQAT-IEBWSBKVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151747   

LigandPNGBDBM50151747((3S,4R)-4-[4-(2,5-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50:  87nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151747((3S,4R)-4-[4-(2,5-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151747((3S,4R)-4-[4-(2,5-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed