BDBM50157420 CHEMBL183770::Ethyl-{6-[4-(2-isopropyl-phenylsulfanyl)-3-trifluoromethyl-phenyl]-pyrimidin-4-yl}-methyl-amine

SMILES CCN(C)c1cc(ncn1)-c1ccc(Sc2ccccc2C(C)C)c(c1)C(F)(F)F

InChI Key InChIKey=VDCWKOMRFTYIHX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157420   

TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50157420(CHEMBL183770 | Ethyl-{6-[4-(2-isopropyl-phenylsulf...)
Affinity DataIC50:  680nMAssay Description:Inhibitory concentration against integrin LFA-1/ICAM-1 binding complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed