BDBM50166619 CHEMBL425897::N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-2-[4-(methanesulfonylamino-methyl)-phenyl]-N-methyl-acetamide

SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)Cc1ccc(CNS(C)(=O)=O)cc1

InChI Key InChIKey=HLZPUXJHOJGNRM-FCHUYYIVSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50166619   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50166619(CHEMBL425897 | N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-...)
Affinity DataKi:  0.600nMAssay Description:Inhibitory constant against human Opioid receptor kappa using [3H]-diprenorphine as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50166619(CHEMBL425897 | N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-...)
Affinity DataKi:  151nMAssay Description:Inhibitory constant against human Opioid receptor mu 1 using [3H]diprenorphine as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50166619(CHEMBL425897 | N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-...)
Affinity DataKi:  167nMAssay Description:Inhibitory constant against human Opioid receptor delta 1 using [3H]diprenorphine as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50166619(CHEMBL425897 | N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-...)
Affinity DataEC50:  1.20nMAssay Description:Inhibitory constant against human Opioid receptor kappa using [3H]diprenorphine as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed