BDBM50166884 CHEMBL3800583

SMILES O=C(Nc1ccccc1)N1CCC(CC1)c1nc(cs1)C1=NOC(C1)c1ccccc1

InChI Key InChIKey=NRXNZYMGTHIJPX-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50166884   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166884(CHEMBL3800583)
Affinity DataKi:  17.9nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166884(CHEMBL3800583)
Affinity DataKi:  18nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 assessed as enzyme ina...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase(Sus scrofa)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166884(CHEMBL3800583)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of porcine liver esterase using 4-nitrophenyl butyrate substrate assessed as reduction in p-nitrophenol release measured over 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166884(CHEMBL3800583)
Affinity DataIC50:  190nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed