BDBM50175904 8-[(1S,2S)-2-(4-chloro-phenyl)-cyclohexyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL413714

SMILES Clc1ccc(cc1)[C@@H]1CCCC[C@@H]1N1CCC2(CC1)N(CNC2=O)c1ccccc1

InChI Key InChIKey=QKABBYCECKWKGD-GOTSBHOMSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50175904   

TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175904(8-[(1S,2S)-2-(4-chloro-phenyl)-cyclohexyl]-1-pheny...)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT2 cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175904(8-[(1S,2S)-2-(4-chloro-phenyl)-cyclohexyl]-1-pheny...)
Affinity DataEC50:  40nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT1 cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed