BDBM50178520 CHEMBL202892::N-(benzo[d][1,3]dioxol-5-ylmethyl)-5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazol-5-yl)-1,3,4-oxadiazol-2-amine

SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(NCc2ccc3OCOc3c2)o1

InChI Key InChIKey=UQKIMTZGDDFLIL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178520   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50178520(CHEMBL202892 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...)
Affinity DataIC50:  440nMAssay Description:Inhibition of VEGFR1 by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50178520(CHEMBL202892 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of VEGFR2 by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50178520(CHEMBL202892 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...)
Affinity DataIC50:  270nMAssay Description:Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed