BDBM50183544 CHEMBL202644::S-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1-(2-methyl-3-phenylpropyl)piperidine oxalate

SMILES C[C@H](CN1CCC(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1)Cc1ccccc1

InChI Key InChIKey=JGDHAGIXYKLIBE-QHCPKHFHSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50183544   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183544(CHEMBL202644 | S-(+)-4-[2-[bis-(4-fluorophenyl)met...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of [3H]DA uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183544(CHEMBL202644 | S-(+)-4-[2-[bis-(4-fluorophenyl)met...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]RTI-55 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183544(CHEMBL202644 | S-(+)-4-[2-[bis-(4-fluorophenyl)met...)
Affinity DataKi:  100nMAssay Description:Displacement of [125I]RTI-55 from SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183544(CHEMBL202644 | S-(+)-4-[2-[bis-(4-fluorophenyl)met...)
Affinity DataKi:  124nMAssay Description:Inhibition of [3H]5HT uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183544(CHEMBL202644 | S-(+)-4-[2-[bis-(4-fluorophenyl)met...)
Affinity DataKi:  160nMAssay Description:Inhibition of [3H]NE uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183544(CHEMBL202644 | S-(+)-4-[2-[bis-(4-fluorophenyl)met...)
Affinity DataKi:  380nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed