BDBM50185666 (R)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-N-ethyl-2-(4-(methylsulfonyl)phenyl)acetamide::CHEMBL212689
SMILES CCN(C1CCN(CC[C@H](c2ccc(cc2)S(C)(=O)=O)c2cc(F)cc(F)c2)CC1)C(=O)Cc1ccc(cc1)S(C)(=O)=O
InChI Key InChIKey=SCXSQUUTGCWHFU-WJOKGBTCSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50185666
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:Displacement of 3,7-Bis[2-(4-nitro[3,5-3H]phenyl)ethyl]-3,7-diazabicyclo[3.3.1]nonane from human ERG expressed in HEK cells after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of P450 2C19More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of P450 2C9More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of P450 2D6More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Binding affinity to CCR5More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of P450 1A1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human ERG by electrophysiological assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of P450 3A4More data for this Ligand-Target Pair