BDBM50187628 CHEMBL378550::N-(1-(3-cyanophenyl)-3-phenyl-1H-pyrazol-3-yl)benzamide

SMILES O=C(Nc1cc(nn1-c1cccc(c1)C#N)-c1ccccc1)c1ccccc1

InChI Key InChIKey=FWCUCSSOOCMGQY-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187628   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50187628(CHEMBL378550 | N-(1-(3-cyanophenyl)-3-phenyl-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50187628(CHEMBL378550 | N-(1-(3-cyanophenyl)-3-phenyl-1H-py...)
Affinity DataEC50:  117nMAssay Description:Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed