BDBM50188266 7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole::CHEMBL213743
SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1
InChI Key InChIKey=OLLCPXMBOYVHAF-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50188266
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of FLT4 by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PDGFR by HTRF assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of FGFR by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of cMet by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 145nMAssay Description:Inhibition of cKit by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 970nMAssay Description:Inhibition of FLT1 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.78E+4nMAssay Description:Inhibition of Tie2 by HTRF assayMore data for this Ligand-Target Pair