BDBM50188275 6-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-dihydroindeno[1,2-c]pyrazole::CHEMBL441369

SMILES CN1CCN(Cc2ccc-3c(Cc4c-3[nH]nc4-c3ccccc3)c2)CC1

InChI Key InChIKey=JBXRPFUTHPUIRP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188275   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188275(6-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...)
Affinity DataIC50:  708nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188275(6-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...)
Affinity DataIC50:  700nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed