BDBM50188862 CHEMBL377350::rac-8-[1-(2-methyl-propenyl)-cyclohexyl]-4-phenyl-2,8-diaza-spiro[4.5]decan-1-one

SMILES [#6]\[#6](-[#6])=[#6]/C1([#6]-[#6]-[#6]-[#6]-[#6]1)[#7]-1-[#6]-[#6]C2([#6]-[#6]-1)[#6](-[#6]-[#7]-[#6]2=O)-c1ccccc1

InChI Key InChIKey=YGUWHZGNNDRWKA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188862   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188862(CHEMBL377350 | rac-8-[1-(2-methyl-propenyl)-cycloh...)
Affinity DataEC50:  979nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed