BDBM50189570 5-methylene-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]decane::CHEMBL377785

SMILES Cc1ccc(cc1)C1CC2CCC3C1C(=C)CN23

InChI Key InChIKey=BMNNHOAPHMYHIH-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50189570   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189570(5-methylene-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]...)
Affinity DataKi:  7.77nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189570(5-methylene-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]...)
Affinity DataKi:  17.3nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189570(5-methylene-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]...)
Affinity DataKi:  41.0nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189570(5-methylene-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of (-)-[3H]NE uptake at NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed