BDBM50195210 6-(4-hydroxy-3-methoxyphenyl)-3-(5-(piperidin-1-ylmethyl)-1H-indol-2-yl)quinolin-2(1H)-one::CHEMBL220903

SMILES COc1cc(ccc1O)-c1ccc2[nH]c(=O)c(cc2c1)-c1cc2cc(CN3CCCCC3)ccc2[nH]1

InChI Key InChIKey=QSCYNBDSVWIZMP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195210   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195210(6-(4-hydroxy-3-methoxyphenyl)-3-(5-(piperidin-1-yl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CHEK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195210(6-(4-hydroxy-3-methoxyphenyl)-3-(5-(piperidin-1-yl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Release of camptothecin-induced cell cycle arrest in NCI-H1299 cells mediated by CHEK1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed