BDBM50202114 CHEMBL386212::H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle-Asp-Phe-H

SMILES CCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@H](Cc1cc2ccccc2[nH]1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=KYWMQIRORZGHDH-QOIWPSRPSA-N

Data  6 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50202114   

TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50202114(CHEMBL386212 | H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50202114(CHEMBL386212 | H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle...)
Affinity DataKi:  13nMAssay Description:Activity at rat mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50202114(CHEMBL386212 | H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50202114(CHEMBL386212 | H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle...)
Affinity DataKi:  7.00E+3nMAssay Description:Displacement of [125I]CCK8-SO3 from human CCK1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50202114(CHEMBL386212 | H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle...)
Affinity DataKi:  7.70E+3nMAssay Description:Displacement of [125I]CCK8-SO3 from human CCK2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50202114(CHEMBL386212 | H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle...)
Affinity DataKi:  7.70E+3nMAssay Description:Displacement of [125I]CCK8-SO3 from human CCK2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50202114(CHEMBL386212 | H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle...)
Affinity DataIC50:  12nMAssay Description:Activity at delta opioid receptor in ICR mouse by MVD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50202114(CHEMBL386212 | H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle...)
Affinity DataIC50:  93nMAssay Description:Activity at mu opioid receptor assessed as contraction of electrically-stimulated Hartley guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50202114(CHEMBL386212 | H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle...)
Affinity DataIC50:  5.15nMAssay Description:Displacement of [125I]CCK8-SO3 from human CCK1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50202114(CHEMBL386212 | H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle...)
Affinity DataIC50:  20nMAssay Description:Activity at human delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50202114(CHEMBL386212 | H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle...)
Affinity DataIC50:  74nMAssay Description:Activity at rat mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed