BDBM50202734 CHEMBL232542::N-(4-(4-amino-7-(3-(diethylamino)prop-1-enyl)thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide

SMILES CCN(CC)C\C=C\c1cnc(N)c2c(csc12)-c1ccc(NC(=O)c2cc3ccccc3n2C)c(OC)c1

InChI Key InChIKey=HFNVVIKLQRUGQK-PKNBQFBNSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50202734   

TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(CHEMBL232542 | N-(4-(4-amino-7-(3-(diethylamino)pr...)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of FgrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(CHEMBL232542 | N-(4-(4-amino-7-(3-(diethylamino)pr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(CHEMBL232542 | N-(4-(4-amino-7-(3-(diethylamino)pr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(CHEMBL232542 | N-(4-(4-amino-7-(3-(diethylamino)pr...)
Affinity DataIC50:  290nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(CHEMBL232542 | N-(4-(4-amino-7-(3-(diethylamino)pr...)
Affinity DataIC50:  9.05E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(CHEMBL232542 | N-(4-(4-amino-7-(3-(diethylamino)pr...)
Affinity DataIC50:  4.41E+4nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(CHEMBL232542 | N-(4-(4-amino-7-(3-(diethylamino)pr...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50202734(CHEMBL232542 | N-(4-(4-amino-7-(3-(diethylamino)pr...)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed