BDBM50206157 CHEMBL398568::N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzo[b]thiophene-2-carboxamide, 15::N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzo[b]thiophene-2-carboxamide::N-(2-(4-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzo[b]thiophene-2-carboxamide

SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cc2ccccc2s1

InChI Key InChIKey=NHABJQWMJCBJAR-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206157   

TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50206157(CHEMBL398568 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  100nMT: 2°CAssay Description:PLD in vitro enzymatic assay using phospholipase D1(PLD1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50206157(CHEMBL398568 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  340nMT: 2°CAssay Description:PLD in vitro enzymatic assay using phospholipase D2(PLD2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206157(CHEMBL398568 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50206157(CHEMBL398568 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo...)
Affinity DataEC50:  14nMT: 2°CAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50206157(CHEMBL398568 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo...)
Affinity DataEC50:  210nMT: 2°CAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50206157(CHEMBL398568 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  1.00E+3nMT: 2°CAssay Description:Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed