BDBM50209150 2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen-3-yl]-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-acetamide::CHEMBL245769

SMILES COCC(=O)Nc1cccc-2c1Cc1c-2n[nH]c1-c1csc(c1)C#CCOc1ccccc1

InChI Key InChIKey=ZKHOXOSYKYODTH-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50209150   

TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50:  2.08E+4nMAssay Description:Inhibition of Lyn by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50:  1.37E+4nMAssay Description:Inhibition of Fyn by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50:  4.33E+4nMAssay Description:Inhibition of Src by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50:  113nMAssay Description:Inhibition of CSF1R by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50:  4.06E+4nMAssay Description:Inhibition of Tie2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50:  710nMAssay Description:Inhibition of Flt1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50:  175nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50:  153nMAssay Description:Inhibition of Flt3 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50:  53nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50:  3.03E+4nMAssay Description:Inhibition of Hck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed